Prostatitis
Overview
Prostatitis is a disorder of the prostate gland usually associated with inflammation. Prostatitis often causes
painful or difficult urination, as well as pain in the groin, pelvic area or genitals. Bacterial infections cause
some but not all cases of prostatitis.
The prostate gland, about the size of a walnut, is located just below the bladder in men. It surrounds the top
portion of the tube that drains urine from the bladder (urethra). The prostate and other sex glands produce the
fluid that transports sperm during ejaculation (semen).
Types
There are generally four types of prostatitis:
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Acute bacterial prostatitis,a bacterial infection of the prostate usually with sudden,
severe symptoms
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Chronic bacterial prostatitis,ongoing or recurring bacterial infection usually with less
severe symptoms
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Chronic prostatitis/chronic pelvic pain syndrome,ongoing or recurring pelvic pain and
urinary tract symptoms with no evidence of infection
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Asymptomatic inflammatory prostatitis,signs of an inflamed prostate with no symptoms
Symptoms
Signs and symptoms of prostatitis can vary depending on the type of disorder. They may include:
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Pain or burning sensation when urinating (dysuria)
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Difficulty urinating, such as dribbling or hesitant urination
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Frequent urination, particularly at night (nocturia)
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Urgent need to urinate
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Cloudy urine
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Blood in the urine
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Pain in the abdomen, groin or lower back
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Pain in the area between the scrotum and rectum (perineum)
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Pain or discomfort of the penis or testicles
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Painful ejaculation
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Fever, chills, muscle aches and other flu-like symptoms (with acute bacterial prostatitis)
Causes
Prostate gland
Causes vary depending on the type of prostatitis.
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Acute bacterial prostatitisis usually caused by common strains of bacteria. The infection
may have spread from other parts of the urinary or reproductive systems.
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Chronic bacterial prostatitisgenerally has the same cause as acute bacterial infection. It
may occur when treatment for an acute infection isn't long enough or fails to kill all the bacteria.
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Chronic prostatitis/chronic pelvic pain syndromeis not well understood. Research suggests
that multiple factors may collectively play a role. These include previous infection, nervous system
dysfunction, immune system dysfunction, psychological stress or irregular hormone activity.
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Asymptomatic inflammatory prostatitis,which has no known cause, is generally found only
during an exam for other medical conditions and is not treated.
Risk factors
Risk factors for prostatitis include:
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Young or middle-aged adulthood
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Previous prostatitis
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Infection of the urinary or reproductive system
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HIV infection or AIDS
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Use of a tube inserted into the urethra to drain the bladder (urinary catheter)
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Diagnostic sampling of prostate tissue (biopsy)
Additional risk factors for chronic prostatitis/chronic pelvic pain syndrome may include:
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Psychological stress
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Nerve damage in the pelvic region due to surgery or trauma
Complications
Complications of acute or chronic prostatitis can include:
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Bacterial infection of the blood (bacteremia)
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Inflammation of the coiled tube attached to the back of the testicle (epididymitis)
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Pus-filled cavity in the prostate (prostatic abscess)
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Infection that spreads to the upper pelvic bone or lower spine
Complications of chronic prostatitis/chronic pelvic pain syndrome may include:
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Anxiety or depression
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Sexual dysfunction, such as the inability to get and maintain an erection (erectile dysfunction)
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Changes in sperm and semen that may cause infertility
There's no direct evidence that prostatitis can lead to prostate cancer. Researchers are investigating whether
chronic inflammation of the prostate is a risk factor for cancer.
Diagnosis
The symptoms associated with prostatitis can be caused by a number of conditions. You may be referred to a specialist
in urinary and reproductive system disorders (urologist). Your health care provider will conduct a physical exam,
review your symptoms and medical history, and order tests to determine the cause and rule out certain conditions.
Test for diagnosing bacterial infections
Diagnostic tests to assess for infection will likely include:
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Digital rectal exam.With this procedure, your health care provider inserts a lubricated,
gloved finger into your rectum to detect inflammation of the prostate.
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Urine test.You'll need to provide a urine sample to be tested for the presence and type of
bacterial infection.
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Blood test.Blood samples may be tested for signs of infection and other prostate problems.
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Prostatic specimen test.In some cases, a health care provider may gently massage the
prostate during a rectal exam to release prostate fluid into your urethra. A urine sample after the massage
expels the prostate fluid for bacterial testing.
Other tests
If initial tests show no sign of infection, you may undergo other tests, including:
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Urodynamic tests.A variety of tests can be used to measure how well the bladder and urethra
hold and release urine. These tests can help characterize problems with urinating and identify the source of
problems.
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Imaging tests may be ordered for identifying irregularities in the prostate, abnormal growths or other
problems in the pelvic region that may be contributing to pain.
Treatment
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Treatment for prostatitis depends on the specific type diagnosed and your symptoms.
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Treating infection
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If you have acute or chronic bacterial prostatitis, you'll take antibiotics. Acute disease may require
intravenous (IV) antibiotics in the hospital for a short period. The entire course of antibiotic treatment
is usually 4 to 6 weeks — or longer in some cases. Taking all the prescribed medication is important
for eliminating the infection and reducing the risk of chronic bacterial prostatitis.
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Treating urinary symptoms
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Medications, called alpha-blockers, help relax the bladder neck and the muscle fibers where your prostate
joins your bladder. This treatment might ease urinary symptoms, such as painful or difficult urination.
While this is commonly prescribed for men with chronic prostatitis/chronic pelvic pain syndrome, it may be
prescribed to relieve urinary symptoms of bacterial infections.
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Treating pain
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Your health care provider may prescribe pain medication or recommend nonprescription drugs, such as
acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others).
Managing psychological symptoms
Your health care provider may recommend psychotherapy with a mental health care professional to help you manage
stress, depression or anxiety that may be associated with chronic pain.