Kidney Stones
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Medical Management
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Minimally Invasive Treatment – PCNL, miniPCNL, RIRS
Kidney stones (also called renal calculi, nephrolithiasis or urolithiasis) are hard deposits made of minerals and
salts that form inside your kidneys. Dr. Priyank Kothari is Best Doctor For Renal Stone Disease Treatment in South Mumbai
Diet, excess body weight, some medical conditions, and certain supplements and medications are among the many causes
of kidney stones. Kidney stones can affect any part of your urinary tract — from your kidneys to your bladder.
Often, stones form when the urine becomes concentrated, allowing minerals to crystallize and stick together.
Passing kidney stones can be quite painful, but the stones usually cause no permanent damage if they're recognized in
a timely fashion. Depending on your situation, you may need nothing more than to take pain medication and drink lots
of water to pass a kidney stone. In other instances — for example, if stones become lodged in the urinary
tract, are associated with a urinary infection or cause complications — surgery may be needed.
We may recommend preventive treatment to reduce your risk of recurrent kidney stones if you're at increased
risk of developing them again. Dr. Priyank Kothari is Best Doctor For Renal Stone Disease Treatment in South Mumbai
Symptoms
A kidney stone usually will not cause symptoms until it moves around within the kidney or passes into one of the
ureters. The ureters are the tubes that connect the kidneys and bladder.
If a kidney stone becomes lodged in the ureters, it may block the flow of urine and cause the kidney to swell and the
ureter to spasm, which can be very painful. At that point, you may experience these symptoms:
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Severe, sharp pain in the side and back, below the ribs
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Pain that radiates to the lower abdomen and groin
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Pain that comes in waves and fluctuates in intensity
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Pain or burning sensation while urinating
Other signs and symptoms may include:
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Pink, red or brown urine
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Cloudy or foul-smelling urine
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A persistent need to urinate, urinating more often than usual or urinating in small amounts
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Nausea and vomiting
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Fever and chills if an infection is present
Pain caused by a kidney stone may change — for instance, shifting to a different location or increasing in
intensity — as the stone moves through your urinary tract.
Causes
Kidney stones often have no definite, single cause, although several factors may increase your risk.
Kidney stones form when your urine contains more crystal-forming substances — such as calcium, oxalate and uric
acid — than the fluid in your urine can dilute. At the same time, your urine may lack substances that prevent
crystals from sticking together, creating an ideal environment for kidney stones to form. Dr. Priyank Kothari is Best Doctor For Renal Stone Disease Treatment in South Mumbai
Types of kidney stones
Knowing the type of kidney stone you have helps determine its cause, and may give clues on how to reduce your risk of
getting more kidney stones. If possible, try to save your kidney stone if you pass one so that you can bring it to
your doctor for analysis.
Types of kidney stones include:
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Calcium stones.Most kidney stones are calcium stones, usually in the form of calcium
oxalate. Oxalate is a substance made daily by your liver or absorbed from your diet. Certain fruits and
vegetables, as well as nuts and chocolate, have high oxalate content.
Dietary factors, high doses of vitamin D, intestinal bypass surgery and several metabolic disorders can increase the
concentration of calcium or oxalate in urine.
Calcium stones may also occur in the form of calcium phosphate. This type of stone is more common in metabolic
conditions, such as renal tubular acidosis. It may also be associated with certain medications used to treat
migraines or seizures, such as topiramate .
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Struvite stones.Struvite stones form in response to a urinary tract infection. These stones
can grow quickly and become quite large, sometimes with few symptoms or little warning.
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Uric acid stones.Uric acid stones can form in people who lose too much fluid because of
chronic diarrhea or malabsorption, those who eat a high-protein diet, and those with diabetes or metabolic
syndrome. Certain genetic factors also may increase your risk of uric acid stones.
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Cystine stones.These stones form in people with a hereditary disorder called cystinuria
that causes the kidneys to excrete too much of a specific amino acid.
Risk factors
Factors that increase your risk of developing kidney stones include:
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Family or personal history.If someone in your family has had kidney stones, you're more
likely to develop stones, too. If you've already had one or more kidney stones, you're at increased risk of
developing another.
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Not drinking enough water each day can increase your risk of kidney stones. People who live in warm, dry
climates and those who sweat a lot may be at higher risk than others.
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Certain diets.Eating a diet that's high in protein, sodium (salt) and sugar may increase
your risk of some types of kidney stones. This is especially true with a high-sodium diet. Too much salt in
your diet increases the amount of calcium your kidneys must filter and significantly increases your risk of
kidney stones.
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High body mass index (BMI), large waist size and weight gain have been linked to an increased risk of kidney
stones.
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Digestive diseases and surgery.Gastric bypass surgery, inflammatory bowel disease or
chronic diarrhea can cause changes in the digestive process that affect your absorption of calcium and
water, increasing the amounts of stone-forming substances in your urine.
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Other medical conditionssuch as renal tubular acidosis, cystinuria, hyperparathyroidism and
repeated urinary tract infections also can increase your risk of kidney stones.
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Certain supplements and medications,such as vitamin C, dietary supplements, laxatives (when
used excessively), calcium-based antacids, and certain medications used to treat migraines or depression,
can increase your risk of kidney stones.
Diagnosis
If your doctor suspects that you have a kidney stone, you may have diagnostic tests and procedures, such as:
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Blood testing.Blood tests may reveal too much calcium or uric acid in your blood. Blood
test results help monitor the health of your kidneys and may lead your doctor to check for other medical
conditions.
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Urine testing.The 24-hour urine collection test may show that you're excreting too many
stone-forming minerals or too few stone-preventing substances. For this test, your doctor may request that
you perform two urine collections over two consecutive days.
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Imaging tests may show kidney stones in your urinary tract. High-speed or dual energy computerized
tomography (CT) may reveal even tiny stones. Simple abdominal X-rays are used less frequently because this
kind of imaging test can miss small kidney stones.
Ultrasound, a noninvasive test that is quick and easy to perform, is another imaging option to diagnose kidney
stones.
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Analysis of passed stones.You may be asked to urinate through a strainer to catch stones
that you pass. Lab analysis will reveal the makeup of your kidney stones. Your doctor uses this information
to determine what's causing your kidney stones and to form a plan to prevent more kidney stones.
Treatment
Treatment for kidney stones varies, depending on the type of stone and the cause.
Small stones with minimal symptoms
Most small kidney stones won't require invasive treatment. You may be able to pass a small stone by:
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Drinking water.Drinking as much as 2 to 3 quarts (1.8 to 3.6 liters) a day will keep your
urine dilute and may prevent stones from forming. Unless your doctor tells you otherwise, drink enough fluid
— ideally mostly water — to produce clear or nearly clear urine.
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Pain relievers.Passing a small stone can cause some discomfort. To relieve mild pain, your
doctor may recommend pain relievers such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve).
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Medical therapy.Your doctor may give you a medication to help pass your kidney stone. This
type of medication, known as an alpha blocker, relaxes the muscles in your ureter, helping you pass the
kidney stone more quickly and with less pain. Examples of alpha blockers include tamsulosin (Flomax) and the
drug combination dutasteride and tamsulosin (Jalyn).
Large stones and those that cause symptoms
Kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract
infections may require more-extensive treatment. Procedures may include:
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Using sound waves to break up stones.For certain kidney stones — depending on size
and location — your doctor may recommend a procedure called extracorporeal shock wave lithotripsy
(ESWL).
ESWL uses sound waves to create strong vibrations (shock waves) that break the stones into tiny pieces that can
be passed in your urine. The procedure lasts about 45 to 60 minutes and can cause moderate pain, so you may be under
sedation or light anesthesia to make you comfortable.
ESWL can cause blood in the urine, bruising on the back or abdomen, bleeding around the kidney and other
adjacent organs, and discomfort as the stone fragments pass through the urinary tract.
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Surgery to remove very large stones in the kidney.A procedure called percutaneous
nephrolithotomy (nef-row-lih-THOT-uh-me) involves surgically removing a kidney stone using small telescopes
and instruments inserted through a small incision in your back.
You will receive general anesthesia during the surgery and be in the hospital for one to two days while you recover.
Your doctor may recommend this surgery if ESWL is unsuccessful.
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Using a scope to remove stones.To remove a smaller stone in your ureter or kidney, your
doctor may pass a thin lighted tube (ureteroscope) equipped with a camera through your urethra and bladder
to your ureter.
Once the stone is located, special tools can snare the stone or break it into pieces that will pass in your urine.
Your doctor may then place a small tube (stent) in the ureter to relieve swelling and promote healing. You may need
general or local anesthesia during this procedure.
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Parathyroid gland surgery.Some calcium phosphate stones are caused by overactive
parathyroid glands, which are located on the four corners of your thyroid gland, just below your Adam's
apple. When these glands produce too much parathyroid hormone (hyperparathyroidism), your calcium levels can
become too high and kidney stones may form as a result.
Hyperparathyroidism sometimes occurs when a small, benign tumor forms in one of your parathyroid glands or you
develop another condition that leads these glands to produce more parathyroid hormone. Removing the growth from the
gland stops the formation of kidney stones. Or your doctor may recommend treatment of the condition that's causing
your parathyroid gland to overproduce the hormone.
Prevention
Prevention of kidney stones may include a combination of lifestyle changes and medications.
Lifestyle changes
You may reduce your risk of kidney stones if you:
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Drink water throughout the day.For people with a history of kidney stones, doctors usually
recommend drinking enough fluids to pass about 2.1 quarts (2 liters) of urine a day. Your doctor may ask
that you measure your urine output to make sure that you're drinking enough water.
If you live in a hot, dry climate or you exercise frequently, you may need to drink even more water to produce enough
urine. If your urine is light and clear, you're likely drinking enough water.
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Eat fewer oxalate-rich foods.If you tend to form calcium oxalate stones, your doctor may
recommend restricting foods rich in oxalates. These include rhubarb, beets, okra, spinach, Swiss chard,
sweet potatoes, nuts, tea, chocolate, black pepper and soy products.
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Choose a diet low in salt and animal protein.Reduce the amount of salt you eat and choose
nonanimal protein sources, such as legumes. Consider using a salt substitute, such as Mrs. Dash.
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Continue eating calcium-rich foods, but use caution with calcium supplements.Calcium in
food doesn't have an effect on your risk of kidney stones. Continue eating calcium-rich foods unless your
doctor advises otherwise.
Ask your doctor before taking calcium supplements, as these have been linked to increased risk of kidney stones. You
may reduce the risk by taking supplements with meals. Diets low in calcium can increase kidney stone formation in
some people.
Ask your doctor for a referral to a dietitian who can help you develop an eating plan that reduces your risk of
kidney stones.
Medications
Medications can control the amount of minerals and salts in the urine and may be helpful in people who form certain
kinds of stones. The type of medication your doctor prescribes will depend on the kind of kidney stones you have.
Here are some examples:
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Calcium stones.To help prevent calcium stones from forming, your doctor may prescribe a
thiazide diuretic or a phosphate-containing preparation.
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Uric acid stones.Your doctor may prescribe allopurinol (Zyloprim, Aloprim) to reduce uric
acid levels in your blood and urine and a medicine to keep your urine alkaline. In some cases, allopurinol
and an alkalizing agent may dissolve the uric acid stones. Dr. Priyank Kothari is Best Doctor For Renal Stone Disease Treatment in South Mumbai
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Struvite stones.To prevent struvite stones, your doctor may recommend strategies to keep
your urine free of bacteria that cause infection, including drinking fluids to maintain good urine flow and
frequent voiding. In rare cases long-term use of antibiotics in small or intermittent doses may help achieve
this goal. For instance, your doctor may recommend an antibiotic before and for a while after surgery to
treat your kidney stones.
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Cystine stones.Along with suggesting a diet lower in salt and protein, your doctor may
recommend that you drink more fluids so that you produce a lot more urine. If that alone doesn't help, your
doctor may also prescribe a medication that increases the solubility of cystine in your urine. Dr. Priyank Kothari is Best Doctor For Renal Stone Disease Treatment in South Mumbai
Surgical Treatment
Percutaneous Nephrolithomy (PCNL) (Minimally Invasive)
Key hole surgery – Mini PCNL – when stone size is small
RIRS – Retrograde Intrarenal Surgery
For multiple stones in different positions in the kidney